Home/Blog / Understanding Biostimulators and Biorejuvenators: What You Need to Know

As the body ages, its natural regenerative processes slow down, leading to skin laxity, volume loss, and other signs of aging. Advanced injectable treatments like biostimulators and biorejuvenators offer a way to restore volume, rejuvenate the skin, and stimulate the body’s natural healing responses. But how do these treatments differ, and how can they be used to achieve natural-looking results?

At KMP Aesthetics, all of our carefully selected biostimulators, biorejuvenator products and devices can restore your skin’s youthful structure and texture. Each works in a slightly different way clinically on different skin types. Our experts will evaluate your specific needs and select a product or combination of treatments and products over time to maximize your results in a way that is specific to you. Below, we’ll discuss what injectable biostimulators and biorejuvenators are, how they work, and what results you can expect.

Biostimulators: Creating a Stimulus for Collagen Growth

Biostimulators are injectable treatments designed to stimulate the body’s natural collagen and elastin production. These treatments work by creating a stimulus within the tissue that triggers collagen synthesis, leading to gradual improvements in skin texture, volume, and elasticity. Biostimulators typically produce gradual results, with effects becoming more noticeable after several weeks. After the biostimulating product is administered, it has a response curve and then the results can either be left to naturally wear off, or they can be layered over time piggybacking the collagen results.

Common biostimulators like Sculptra® Aesthetic and hyperdiluted Radiesse® use different mechanisms to revitalize the appearance, as outlined below:

Biorejuvenators: Accelerating Healing and Enhancing Natural Beauty Using Your Own Internal Blueprint

While biostimulators create a stimulus for collagen and elastin production, biorejuvenators work by directly targeting the cellular messengers that are responsible for the skin’s natural healing and tissue growth mechanisms. These treatments focus on improving skin texture, hydration, radiance and abundance while supporting the skin’s regeneration at a deeper level. Every section of you is composed of a unique combination of tissue components that arrange in functional layers to provide functional beauty. As we age, our ability to trigger our innate healing mechanisms using our natural stem cells is diminished. This leads to tangled collagen fibers, a dwindling blood supply and tissue that lacks both flexibility and surface tension.

Biorejuvenators – such as Renuva® and Platelet-Derived Growth Factor (PDGF+) – emphasize a healing approach that works with your genetic blueprint specific to each targeted area to restore a youthful, vibrant appearance. This approach allows for functional improvement in the tissue layers they affect and their blood supply, so it not only enhances your beauty, it helps the body hold onto these changes over time. The results from these treatments tend to last longer and develop more quickly than those of biostimulators, and less downtime is typically required for normal undamaged tissue. In cases where it is used to heal a scar or previously injured anatomical layers, it will elicit a longer healing cascade response to get more healing and revision to the treatment area.

Biostimulators vs. Biorejuvenators: How They Differ

The key difference between biostimulators and biorejuvenators lies in their approach:

Why Choose Biostimulators and Biorejuvenators?

Both biostimulators and biorejuvenators offer unique benefits:

Biorejuvenator treatments can specifically complement neuromodulator injectable treatments (like BOTOX® Cosmetic and DAXXIFY™) beautifully. They work together with the neuromodulators to relax overly tense tissue while the biorejuvenators enhance the skin’s natural ability to maintain an uncreased/untangled appearance. This refreshed appearance is uniquely your own, and over time, it can last longer and longer with repeat layers and treatments.

Scuptra®, Radiesse® and particularly PDGF+ can work to enhance laser and energy device treatments like SylfirmX treatments and Halo™ ablative/non-ablative skin resurfacing. Not only can PDGF+ be applied to the exposed channels post-procedure for enhancement of the induction of healing cascade components and overall results, but Sculptra® and hyperdiluted Radiesse® can be injected into the treatment area post-procedurally as well. 

At KMP Aesthetics, we are proud to offer advanced PDGF+ therapy options and Dr. Kevan Petterson, DNP, ARNP stands out as the Consummate Provider of Advanced PDGF+ Treatments locally and globally. He leads KMP Aesthetics to develop novel, safe and effective approaches and applications using PDGF+ which include: Inflammation Banding of the Body From Head to Toe, and Tailored Concentration Layering of the Face, Neck and Body to gradually but dramatically heal your unique anatomical and structural aging. Without the remnants of previous trauma, your tissue is once again able to achieve the natural shape, lift and movement-related dynamics that you remember staring back at you in the mirror.

The integration of biogenerative and bio-rejuvenative treatments into your aesthetic treatment plan has never been more easy, exciting, and gratifying. Learn why our patients are sharing our addiction and passion for biorejuvenation with PGDF+ carefully woven through your specific treatment pathway. It feels good to know you’re taking steps to help your body heal beautifully instead of counting on placing a pretty band-aid over your key concern. Whether you’re looking for skin rejuvenation, hair restoration, or simply enhancing your skin’s natural glow, advanced PDGF+ treatments can help you achieve your aesthetic goals with lasting, natural results.

Don’t wait to experience the transformative benefits of advanced PDGF+ therapy and biorejuvenation. Contact KMP Aesthetics today to schedule your consultation and discover how our treatments can enhance your beauty and well-being.